Potentiating CAR-T cell function in the immunosuppressive tumor microenvironment by inverting the TGF-β signal
Zheng Shen, Xuan Che, Kai Zhang, Yun Bai, Hongkui Deng
Topics & Concepts
Tumor microenvironmentFunction (biology)Cell biologyTransforming growth factorGain of functionCancer researchSignal transductionChemistryTumor cellsBiologyGenePhenotypeBiochemistryCAR-T cell therapy research