Electrochemical Palladium‐Catalyzed Oxidative Carbonylation‐Cyclization of Enallenols
Jianwei Zhang, Biswanath Das, Oscar Verho, Jan‐E. Bäckvall
Abstract
Herein, we report an electrochemical oxidative palladium-catalyzed carbonylation-carbocyclization of enallenols to afford γ-lactones and spirolactones, which proceeds with excellent chemoselectivity. Interestingly, electrocatalysis was found to have an accelerating effect on the rate of the tandem process, leading to a more efficient reaction than that under chemical redox conditions.
Topics & Concepts
ChemoselectivityCarbonylationCatalysisPalladiumChemistryElectrochemistryOxidative phosphorylationElectrocatalystRedoxCombinatorial chemistryTandemOrganic chemistryCarbon monoxideElectrodeMaterials scienceBiochemistryComposite materialPhysical chemistryCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsRadical Photochemical Reactions