CESSAT: A chemical additive-enhanced single-step accurate CRISPR/Cas13 testing system for field-deployable ultrasensitive detection and genotyping of SARS-CoV-2 variants of concern
Yunxiang Wang, Hong Chen, Huixia Gao, Hongjuan Wei, Yuling Wang, Kai Mu, Liyan Liu, Erhei Dai, Zhen Rong, Shengqi Wang
Topics & Concepts
CRISPRGenotypingDetection limitSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)ReagentRecombinase Polymerase AmplificationComputational biologyChemistryNanotechnologyCoronavirus disease 2019 (COVID-19)BiologyChromatographyDNAMaterials scienceInfectious disease (medical specialty)GenotypeLoop-mediated isothermal amplificationGeneticsGeneMedicineDiseasePathologyPhysical chemistryCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection