New Route to the Synthesis of Benzamide-Based 5-Aminopyrazoles and Their Fused Heterocycles Showing Remarkable Antiavian Influenza Virus Activity
Ali M. S. Hebishy, Hagar T. Salama, Galal H. Elgemeie
Abstract
were found to possess significant antiviral activities against bird flu influenza (H5N1) with viral reduction in the range of 85-65%.
Topics & Concepts
ChemistryMalononitrileAlkylationBenzamideMedicinal chemistryNuclear magnetic resonance spectroscopyOrganic chemistryCatalysisSynthesis and Characterization of Heterocyclic CompoundsSynthesis of heterocyclic compoundsSynthesis and Biological Evaluation