Ag‐Catalyzed Cyclization of Arylboronic Acids with Elemental Selenium for the Synthesis of Selenaheterocycles
Xue Zhang, Xiaobo Huang, Wenxia Gao, Yunbing Zhou, Miaochang Liu, Huayue Wu
Abstract
Abstract A general method for the synthesis of five‐membered and six‐membered selenaheterocycles through Ag‐catalyzed C−Se bond‐forming reaction is reported. This reaction proceeds via intramolecular cyclization of arylboronic acids with selenium powder. Preliminary mechanism studies demonstrate that this transformation involves a selenium‐centred radical intermediate. magnified image
Topics & Concepts
ChemistrySeleniumIntramolecular forceCatalysisTransformation (genetics)Combinatorial chemistryMedicinal chemistryStereochemistryOrganic chemistryGeneBiochemistryOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods