Low‐Voltage‐Driven Electrochemical Aerobic Oxygenation with Flavin Catalysis: Chemoselective Synthesis of Sulfoxides from Sulfides
Taiga Mizushima, Marina Oka, Yasushi Imada, Hiroki Iida
Abstract
Abstract The chemoselective electrochemical oxygenation of sulfides to sulfoxides is performed using a biomimetic flavin catalyst that enables the activation of molecular oxygen under a low cathode potential. Diverse functional groups, including alcohols, ketones, aldehydes, cyclopropane, carboxylic acids, pyridine, alkenes, and alkynes, are well tolerated under low‐voltage electrolytic conditions. magnified image
Topics & Concepts
ChemistryElectrochemistryFlavin groupCatalysisPyridineCyclopropaneChemoselectivityOxygenationCathodeCombinatorial chemistryOrganic chemistryPhotochemistryElectrodeEcologyBiologyEnzymeRing (chemistry)Physical chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods