Design, synthesis and evaluation of anti-proliferative activity of 2-aryl-4-aminoquinazoline derivatives as EGFR inhibitors
Zhihui Zhou, Jie He, Feiyi Yang, Qingshan Pan, Zunhua Yang, Pengwu Zheng, Shan Xu, Wufu Zhu
Topics & Concepts
ChemistryArylCombinatorial chemistryEGFR inhibitorsStereochemistryPharmacologyBiochemistryEpidermal growth factor receptorOrganic chemistryReceptorAlkylMedicineLung Cancer Treatments and MutationsHER2/EGFR in Cancer ResearchQuinazolinone synthesis and applications