[ABC transporter and its application in synthetic biology].
Junze Qu, Tianhua Chen, Mingdong Yao, Ying Wang, Wenhai Xiao, Bing‐Zhi Li
Abstract
As an ancient and huge family of membrane proteins, ATP-binding cassette transporter (ABC transporter) plays an important physiological role in most organisms. Herein, we introduce the research progress in ABC transporters on the aspects of structural characteristic, transport mechanism and physiological functions. We also focus on the application of ABC transporters in the field of synthetic biology in recent years. Finally, we propose future research needs.
Topics & Concepts
ATP-binding cassette transporterTransporterComputational biologyBiologySynthetic biologyMechanism (biology)BiochemistryGenePhysicsQuantum mechanicsDrug Transport and Resistance MechanismsDNA and Nucleic Acid ChemistryChemical Synthesis and Analysis