Novel artemisinin derivative FO8643 with anti-angiogenic activity inhibits growth and migration of cancer cells via VEGFR2 signaling
Xiaohua Lu, Sebastian Blatt, Mona Dawood, Sabine M. Klauck, Edmond Fleischer, Peer W. Kämmerer, Thomas Efferth
Topics & Concepts
AngiogenesisCancer cellChorioallantoic membraneCancer researchProtein kinase BPI3K/AKT/mTOR pathwayArtemisininMAPK/ERK pathwayKinase insert domain receptorCell growthChemistryBiologyCancerKinaseSignal transductionPharmacologyCell biologyVascular endothelial growth factorVascular endothelial growth factor ABiochemistryImmunologyPlasmodium falciparumVEGF receptorsGeneticsMalariaAngiogenesis and VEGF in CancerCancer Mechanisms and TherapyCytokine Signaling Pathways and Interactions