Cation-Responsive and Photocleavable Hydrogels from Noncanonical Amphiphilic DNA Nanostructures
Giacomo Fabrini, Aisling Minard, Ryan A. Brady, Marco Di Antonio, Lorenzo Di Michele
Abstract
ions. Furthermore, the hydrogel aggregates can be photo-disassembled upon near-UV irradiation in the presence of a porphyrin photosensitizer. The combined reversibility of assembly, responsiveness, and cargo-loading capabilities of the hydrophobic moieties make Quad-Stars a promising candidate for biosensors and responsive drug delivery carriers.
Topics & Concepts
AmphiphileSelf-healing hydrogelsDNANanostructureChemistryNanotechnologyMaterials scienceBiophysicsPolymer chemistryPolymerCopolymerBiochemistryOrganic chemistryBiologyAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryGold and Silver Nanoparticles Synthesis and Applications