Terminal α2,6-sialylation of epidermal growth factor receptor modulates antibody therapy response of colorectal cancer cells
Joana G. Rodrigues, Henrique O. Duarte, Catarina Gomes, Meritxell Balmaña, Álvaro M. Martins, Paul J. Hensbergen, Arnoud H. de Ru, Jorge Lima, André Albergaria, Peter A. van Veelen, Manfred Wuhrer, Joana Gomes, Celso A. Reis
Topics & Concepts
CetuximabEpidermal growth factor receptorCancer researchColorectal cancerMonoclonal antibodyEpidermal growth factorTargeted therapyCancerDownregulation and upregulationReceptorMedicineBiologyImmunologyAntibodyInternal medicineBiochemistryGeneGlycosylation and Glycoproteins ResearchHER2/EGFR in Cancer ResearchGalectins and Cancer Biology