7-hydroxycoumarin modulates Nrf2/HO-1 and microRNA-34a/SIRT1 signaling and prevents cisplatin-induced oxidative stress, inflammation, and kidney injury in rats
Demiana H. Sami, Ayman S. Soliman, Akef A. Khowailed, Emad H. M. Hassanein, Emadeldin M. Kamel, Ayman M. Mahmoud
Topics & Concepts
Oxidative stressNephrotoxicityPharmacologyReactive oxygen speciesKidneyCreatinineInflammationMalondialdehydeChemistryAcute kidney injuryNitric oxideApoptosisAntioxidantMedicineInternal medicineBiochemistryChemotherapy-induced organ toxicity mitigationNeurological Complications and SyndromesAcute Kidney Injury Research