Anticancer strategies by upregulating p53 through inhibition of its ubiquitination by MDM2
Abiodun Anifowose, Ayodeji A. Agbowuro, Xiaoxiao Yang, Binghe Wang
Topics & Concepts
Mdm2ChemistryUbiquitinNegative regulatorRegulatorP53 proteinCancer researchSmall moleculeCell biologyComputational biologyBiochemistryBiologySignal transductionApoptosisGeneProtein Degradation and InhibitorsCancer-related Molecular PathwaysUbiquitin and proteasome pathways