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Unveiling the power of Pueraria lobata: a comprehensive exploration of its medicinal and edible potentials

Baixin Kou, Lingkun Meng, Mengya Zhao, Haidong Wang, Chih-Cheng Lu, Mingming Yan, Guangzhe Li

2025Frontiers in Pharmacology12 citationsDOIOpen Access PDF

Abstract

Background: . In addition, its roots and powder can be made into food. Aim of the study: (PL), summarize the evolution of its medicinal and edible value, and generalize its chemical composition, biosynthetic pathways, metabolism, and biological activity. Materials and Methods: A comprehensive literature search (1975-2025) was conducted across ScienceDirect, Google Scholar, PubMed, Web of Science, CNKI, WFO (www.worldfloraonline.org), MPNS (https://mpsn.kew.org), Changchun University of Chinese Medicine Library collections, and SciFinder. Ancient applications were validated through analysis of classic Chinese medical literature. Results: PL is predominantly found in Asia, Europe, and America, with significant populations in China's Zhejiang, Jiangxi, Jiangsu, Guangdong, and Guangxi provinces. The plant comprises flavonoids, triterpenoids, and coumarins, including isoflavonoids like daidzein and puerarin, which are synthesized via diverse pathways. Metabolites produced from liver or intestinal reactions are crucial to PL's effectiveness. Key components include puerarin, daidzein, genistein, biochanin A, and formononetin. In China, PL is incredibly versatile, being used in a wide range of foods, teas, preservatives, dairy products, Conclusion: Its extensive biological activities benefit the human body, with particular emphasis on liver protection, anti-osteoporosis, and anti-diabetic effects. These attributes highlight the potential for developing health foods, revealing PL's promising prospects in the pharmaceuticals and nutritional healthcare industries.

Topics & Concepts

PuerariaTraditional medicineLobataMedicinePharmacologyAlternative medicinePathologyPhytoestrogen effects and researchBioactive natural compoundsHops Chemistry and Applications