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Design, synthesis, molecular docking and in silico ADMET profile of pyrano[2,3-d]pyrimidine derivatives as antimicrobial and anticancer agents

Nour E. A. Abd El‐Sattar, Khaled El‐Adl, Maher A. El‐Hashash, Samir A. Salama, Mostafa M. Elhady

2021Bioorganic Chemistry82 citationsDOI

Topics & Concepts

ChemistryPyrimidineMalononitrileStereochemistryAntimicrobialPyridineIC50Antibacterial activityDocking (animal)Combinatorial chemistryMedicinal chemistryBiochemistryIn vitroOrganic chemistryBacteriaMedicineGeneticsNursingCatalysisBiologySynthesis and biological activityMulticomponent Synthesis of HeterocyclesSynthesis and Biological Evaluation
Design, synthesis, molecular docking and in silico ADMET profile of pyrano[2,3-d]pyrimidine derivatives as antimicrobial and anticancer agents | Litcius