Rapid quantitation of three synthetic cathinones in urine by magnetic dispersive solid-phase extraction combined with DART-HRMS
Yawen Li, Ru Lian, Feiyu Yang, Zhiru Xu, Fangqi Cao, Rong Wang, Chen Liang, Yurong Zhang
Abstract
, respectively. The correlation coefficients were all greater than 0.99. The precision and deviation of accuracy were all within ±15%, and the stability of the samples was high under various conditions. The method was successfully applied to detect 4-Cl-α-PVP, 4-MPD and β-TH-naphyrone in rat urine after subcutaneous administration. In summary, a fast and convenient detection method was established, providing new and effective technical support for the rapid quantitation of three synthetic cathinones (4-Cl-α-PVP, 4-MPD and β-TH-Naphyrone) for forensic purposes.
Topics & Concepts
ChemistryChromatographyDetection limitSolid phase extractionExtraction (chemistry)UrineResolution (logic)Artificial intelligenceComputer scienceBiochemistryForensic Toxicology and Drug AnalysisAnalytical Chemistry and ChromatographyMass Spectrometry Techniques and Applications