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<i>lon</i> Deletion Impairs Persister Cell Resuscitation in Escherichia coli

Sayed Golam Mohiuddin, Aslan Massahi, Mehmet A. Orman

2022mBio18 citationsDOIOpen Access PDF

Abstract

-deficient persister cells transitioning to a normal cell state. Collectively, our findings highlight the importance of differentiating persister formation mechanisms from resuscitation mechanisms and underscore the critical role of the nonculturable cell state in antibiotic tolerance.

Topics & Concepts

FtsZMultidrug toleranceEscherichia coliBiologySOS responseMicrobiologyViable but nonculturableBacteriaCell divisionCell biologyCellGeneticsBiofilmGeneBacterial Genetics and BiotechnologyAntibiotic Resistance in BacteriaEscherichia coli research studies
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