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PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol

Anna Roubtsova, Damien Garçon, Sandrine Lacoste, Ann Chamberland, Jadwiga Marcinkiewicz, Raphaël Métivier, Thibaud Sotin, Martine Paquette, Sophie Bernard, Bertrand Cariou, Cédric Le May, Marlys L. Koschinsky, Nabil G. Seidah, Annik Prat

2022Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids22 citationsDOIOpen Access PDF

Topics & Concepts

LDL receptorPCSK9EndocrinologyInternal medicineCholesterolBiologyKnockout mouseHMG-CoA reductaseReceptorLipoproteinMedicineBiochemistryReductaseEnzymeLipoproteins and Cardiovascular Health
PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol | Litcius