PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol
Anna Roubtsova, Damien Garçon, Sandrine Lacoste, Ann Chamberland, Jadwiga Marcinkiewicz, Raphaël Métivier, Thibaud Sotin, Martine Paquette, Sophie Bernard, Bertrand Cariou, Cédric Le May, Marlys L. Koschinsky, Nabil G. Seidah, Annik Prat
2022Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids22 citationsDOIOpen Access PDF
Topics & Concepts
LDL receptorPCSK9EndocrinologyInternal medicineCholesterolBiologyKnockout mouseHMG-CoA reductaseReceptorLipoproteinMedicineBiochemistryReductaseEnzymeLipoproteins and Cardiovascular Health