<i>Mycoplasma pneumoniae</i> downregulates RECK to promote matrix metalloproteinase-9 secretion by bronchial epithelial cells
Lianmei Qin, Lu Liu, Yueping Wu, Yi-Wen Chen, Yueyue Wu, Haodang Luo, Yixuan Xi, Feichen Xiu, Jun Hu, Liesong Chen, Ning Wu, Jun He, Yanhua Zeng, Cuiming Zhu, Xiaoxing You
Abstract
downregulated the expression of RECK, thereby increasing MMP-9 activity to modulate the inflammatory response, which could play a role in airway remodelling.
Topics & Concepts
BiologyMycoplasma pneumoniaeInnate immune systemTLR2SecretionMAPK/ERK pathwayTLR4KinaseImmune systemMolecular biologyCell biologyCancer researchSignal transductionImmunologyMedicineBiochemistryPneumoniaInternal medicineInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPneumonia and Respiratory InfectionsPeptidase Inhibition and Analysis