Heterodinuclear Ru–Pt Complexes Bridged with 2,3-Bis(pyridyl)pyrazinyl Ligands: Studies on Kinetics, Deoxyribonucleic Acid/Bovine Serum Albumin Binding and Cleavage, In Vitro Cytotoxicity, and In Vivo Toxicity on Zebrafish Embryo Activities
Rajesh Bellam, Deogratius Jaganyi, Ross S. Robinson
Abstract
could be considered for further development as chemotherapeutic agents against MCF breast cancer cells.
Topics & Concepts
ChemistryBovine serum albuminReactivity (psychology)QuinoxalineStereochemistryQuenching (fluorescence)DNATitrationCytotoxicityIn vitroFluorescenceBiochemistryOrganic chemistryAlternative medicineMedicineQuantum mechanicsPhysicsPathologyMetal complexes synthesis and propertiesSynthesis and Biological EvaluationClick Chemistry and Applications