α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer
Chia-Hao Tung, Meng‐Fan Huang, Chen-Hsien Liang, Yi-Ying Wu, Jiaen Wu, Cheng–Lung Hsu, Yuh‐Ling Chen, Tse-Ming Hong
Abstract
The cytoskeletal linker protein -Catulin has been shown to be important for tumor progression in various cancers. However, its role in the regulation of cancer stemness remains unclear.
Topics & Concepts
Lung cancerCancerCancer researchChemistryBiologyCell biologyMedicinePathologyInternal medicineKruppel-like factors researchGenetic Syndromes and ImprintingCancer-related gene regulation