Dasatinib plus quercetin prevents uterine age-related dysfunction and fibrosis in mice
Marcelo Borges Cavalcante, Tatiana D. Saccon, Allancer Nunes, James L. Kirkland, Tamar Tchkonia, Augusto Schneider, Michał M. Masternak
Abstract
signaling pathway in uterine aging and suggest for the first time a possible anti-fibrotic effect in the uterus of D+Q senolytic therapy.
Topics & Concepts
DasatinibFibrosisMedicineQuercetinInternal medicineOncologyCancer researchBiologyTyrosine kinaseReceptorAntioxidantBiochemistryChronic Myeloid Leukemia TreatmentsEosinophilic Disorders and SyndromesMast cells and histamine