A High-Throughput Method to Prioritize PROTAC Intracellular Target Engagement and Cell Permeability Using NanoBRET
James D. Vasta, Cesear Corona, Matthew B. Robers
Topics & Concepts
Ubiquitin ligaseIntracellularDNA ligaseCellCell biologyUbiquitinChemistryComputational biologyBiologyBiochemistryGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments