Liraglutide Regulates Mitochondrial Quality Control System Through PGC-1α in a Mouse Model of Parkinson’s Disease
Pengyue Wu, Yuxuan Dong, Jinhu Chen, Tianyuan Guan, Bing Cao, Yanqiu Zhang, Yueyan Qi, Zhenlong Guan, Yanqin Wang
Topics & Concepts
MPTPLiraglutideNeuroprotectionMitophagyMFN2Mitochondrial biogenesisDownregulation and upregulationTFAMMitochondrionAutophagyPINK1Cell biologyBiologyEndocrinologyPharmacologymitochondrial fusionApoptosisDopamineBiochemistryMitochondrial DNAGeneType 2 diabetesDiabetes mellitusDopaminergicAdipose Tissue and MetabolismAutophagy in Disease and TherapyPancreatic function and diabetes