A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans
Boyan Zhang, Chenyu Wang, Yue Zhang, Yuan Jiang, Yanguo Qin, Daxin Pang, Guizhen Zhang, He Liu, Zicong Xie, Hongming Yuan, Hongsheng Ouyang, Jincheng Wang, Xiaochun Tang
Topics & Concepts
BiologyDysplasiaSomatic cellPathogenesisMutantMutationTransgeneGeneticsPathologyGeneMedicineImmunologyCell Adhesion Molecules ResearchRenal and related cancersConnective tissue disorders research