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A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans

Boyan Zhang, Chenyu Wang, Yue Zhang, Yuan Jiang, Yanguo Qin, Daxin Pang, Guizhen Zhang, He Liu, Zicong Xie, Hongming Yuan, Hongsheng Ouyang, Jincheng Wang, Xiaochun Tang

2020Bone19 citationsDOI

Topics & Concepts

BiologyDysplasiaSomatic cellPathogenesisMutantMutationTransgeneGeneticsPathologyGeneMedicineImmunologyCell Adhesion Molecules ResearchRenal and related cancersConnective tissue disorders research
A CRISPR-engineered swine model of COL2A1 deficiency recapitulates altered early skeletal developmental defects in humans | Litcius