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Soluble total antigen derived from Toxoplasma gondii tachyzoites increased the expression levels of NLRP1, NLRP3, NLRC4, AIM2, and the release of mature form of IL1β, but downregulated the expression of IL1β and IL18 genes in THP-1cell line

Hossein Pazoki, Hanieh Mohammad Rahimi, Hamed Mirjalali, Maryam Niyyati, Nariman Mosaffa, Seyed Javad Seyed Tabaei, Shabnam Shahrokh, Hamid Asadzadeh Aghdaei, Mohammad Reza Zali

2021Microbial Pathogenesis20 citationsDOI

Topics & Concepts

Toxoplasma gondiiAIM2BiologyIntracellular parasiteToxoplasmosisNLRC4Interleukin 18PopulationMicrobiologyCytokineIntracellularMolecular biologyChemistryInflammasomeCaspase 1ImmunologyAntibodyBiochemistryMedicineInflammationEnvironmental healthToxoplasma gondii Research StudiesInflammasome and immune disordersHeme Oxygenase-1 and Carbon Monoxide
Soluble total antigen derived from Toxoplasma gondii tachyzoites increased the expression levels of NLRP1, NLRP3, NLRC4, AIM2, and the release of mature form of IL1β, but downregulated the expression of IL1β and IL18 genes in THP-1cell line | Litcius