Upregulation of TTYH3 promotes epithelial-to-mesenchymal transition through Wnt/β-catenin signaling and inhibits apoptosis in cholangiocarcinoma
Weijie Xue, Bingzi Dong, Yanjie Zhao, Yixiu Wang, Chenyu Yang, Yuwei Xie, Zhaojian Niu, Chengzhan Zhu
Topics & Concepts
VimentinEpithelial–mesenchymal transitionDNA methylationWnt signaling pathwayDownregulation and upregulationBiologyCancer researchApoptosisCpG siteMethylationWestern blotMolecular biologySignal transductionCell biologyGene expressionImmunohistochemistryImmunologyGeneGeneticsIon channel regulation and functionIon Channels and ReceptorsWnt/β-catenin signaling in development and cancer