Improved predictions of antigen presentation and TCR recognition with MixMHCpred2.2 and PRIME2.0 reveal potent SARS-CoV-2 CD8+ T-cell epitopes
David Gfeller, Julien Schmidt, Giancarlo Croce, Philippe Guillaume, Sara Bobisse, Raphaël Genolet, Lise Queiroz, Julien Cesbron, Julien Racle, Alexandre Harari
Topics & Concepts
EpitopeT-cell receptorHuman leukocyte antigenBiologyAntigenT cellCytotoxic T cellComputational biologyCD8ImmunologyImmunotherapyMonoclonal antibodyImmune systemVirologyAntibodyGeneticsIn vitrovaccines and immunoinformatics approachesImmunotherapy and Immune ResponsesSARS-CoV-2 and COVID-19 Research