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Forensic seized drug analysis: Current challenges and emerging analytical solutions

M.C. Joshi, Edward Sisco

2023Wiley Interdisciplinary Reviews Forensic Science21 citationsDOIOpen Access PDF

Abstract

Abstract Over the past decade, new challenges in seized drug analysis have pushed the limits of existing instrumentation and workflows. These challenges include increasing caseloads, complex samples containing previously unidentified substances, and evolving legal requirements. Traditional approaches to seized drug analysis—such as gas chromatography mass spectrometry, color tests, and Fourier transform infrared spectroscopy—can be insufficient for current challenges, motivating the community to explore new instrumentation or data analysis solutions. However, the road to validation, implementation, and adoption of new technologies and solutions can be arduous. In this overview, we discuss the major challenges facing the seized drug community that can be addressed by advances in analytical approaches and highlight some emerging techniques that have been or could be adopted by laboratories in the near‐term. We also discuss specific hurdles limiting the implementation and adoption of new techniques, and approaches to lower these barriers. This article is categorized under: Forensic Chemistry and Trace Evidence > Controlled and Emerging Drug Compounds Forensic Chemistry and Trace Evidence > Emerging Technologies and Methods Forensic Chemistry and Trace Evidence > Presentation and Evaluation of Forensic Science Output

Topics & Concepts

WorkflowLimitingComputer scienceData scienceInstrumentation (computer programming)Emerging technologiesTRACE (psycholinguistics)Presentation (obstetrics)NanotechnologyRisk analysis (engineering)EngineeringBusinessMaterials scienceMedicineArtificial intelligenceRadiologyOperating systemLinguisticsDatabaseMechanical engineeringPhilosophyMass Spectrometry Techniques and ApplicationsForensic Toxicology and Drug AnalysisMetabolomics and Mass Spectrometry Studies
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