Silk fibroin-based piezoelectric nanofibrous scaffolds for rapid wound healing
Xiaoyang Yue, Zengkai Wang, Hui Shi, Rongrong Wu, Yonghai Feng, Liang Yuan, Shuai Hou, Xiaolu Song, Lei Liu
Abstract
cell proliferation experiments showed that the LN/CNTs/SF-NFSs promoted cell proliferation at a rate of 43%. Accordingly, the mouse wound healing experiments further indicated that they could accelerate the healing of skin wounds in mice that were continuously moving. Therefore, SF-based piezoelectric nanofibrous scaffolds exhibit potential for use in rapid wound healing and this sheds light on smart treatment for tissue engineering in biomedicine.
Topics & Concepts
FibroinElectrospinningNanofiberWound healingBiocompatibilityTissue engineeringMaterials scienceBiomedical engineeringUltimate tensile strengthNanotechnologyIn vivoSILKPolymerComposite materialSurgeryMedicineBiologyMetallurgyBiotechnologySilk-based biomaterials and applicationsElectrospun Nanofibers in Biomedical ApplicationsAdvanced Sensor and Energy Harvesting Materials