Leaky pipes: Tau and apoE implicated in blood-brain barrier dysfunction in Alzheimer disease
Albert A. Davis
Abstract
Concentrations of tight junction proteins correlate with tau and apolipoprotein E in Alzheimer disease brain tissue independent of cerebral amyloid angiopathy.
Topics & Concepts
Apolipoprotein EBlood–brain barrierDiseaseMedicineNeuroscienceAlzheimer's diseasePathologyPsychologyCentral nervous systemBarrier Structure and Function StudiesAlzheimer's disease research and treatmentsNeurological Disease Mechanisms and Treatments