TD-92, a novel erlotinib derivative, depletes tumor-associated macrophages in non-small cell lung cancer via down-regulation of CSF-1R and enhances the anti-tumor effects of anti-PD-1
Chi-Ting Shih, Chung-Wai Shiau, Yen‐Lin Chen, Li-Ju Chen, Tzu-I Chao, Cheng‐Yi Wang, Chao‐Yuan Huang, Man‐Hsin Hung, Kuen‐Feng Chen
Topics & Concepts
Lung cancerImmune systemErlotinibCancer researchTumor microenvironmentLewis lung carcinomaMedicineCancerImmunotherapyPopulationImmune checkpointImmunologyBiologyEpidermal growth factor receptorInternal medicineMetastasisEnvironmental healthCancer Immunotherapy and BiomarkersImmune cells in cancerImmune Cell Function and Interaction