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Microbial metabolites in the gut-brain axis: their impact on depression pathophysiology and treatment

Yawen Li, Tianyi Li, Yaoqing Zhang, Ye Wang, Guojun Wu, Yurong Tan

2025Neuroscience9 citationsDOI

Topics & Concepts

NeurotransmitterNeuroinflammationNeuroprotectionNeuroscienceNeurotransmitter AgentsMetaboliteGut–brain axisNeurochemicalAnimal models of depressionPharmacologyKynurenineBiologyNeuropharmacologyNeurotransmissionAnimal studiesNeuroplasticityMechanism (biology)Kynurenine pathwaySerotoninGut floraMedicineQuinolinic acidMajor depressive disorderMetabolomicsSynaptic plasticityMonoaminergicMonoamine neurotransmitterPathophysiologyGlutamate receptorAnti-Anxiety AgentsBioinformaticsReuptake inhibitorCentral nervous systemBioenergeticsAntidepressantEicosanoid metabolismHomovanillic acidSerotonergicGut microbiota and healthTryptophan and brain disordersGABA and Rice Research
Microbial metabolites in the gut-brain axis: their impact on depression pathophysiology and treatment | Litcius