How the structural properties of the indole derivatives are important in kinase targeted drug design?: A case study on tyrosine kinase inhibitors
Dipayan Mondal, Sk. Abdul Amin, Md. Moinul, Kalpataru Das, Tarun Jha, Shovanlal Gayen
Topics & Concepts
KinaseReceptor tyrosine kinaseTyrosine kinaseDruggabilityBiochemistryChemistryDrug discoveryCell biologyPlatelet-derived growth factor receptorBiologySignal transductionGrowth factorReceptorGeneSynthesis and biological activityPI3K/AKT/mTOR signaling in cancerHER2/EGFR in Cancer Research