Engineering of a zero cross-talk fluorescent polymer nanoprobe for self-referenced ratiometric imaging of lysosomal hypochlorous acid in living cells
Hongqing Wei, Rongjin Zeng, Shenglan Wang, Chonghua Zhang, Shu Chen, Peisheng Zhang, Jian Chen
Abstract
A zero cross-talk fluorescent polymer nanoprobe with a self-referenced ratiometric effect was rationally designed and synthesized for lysosomal hypochlorous acid (HClO) imaging in live cells.
Topics & Concepts
Hypochlorous acidNanoprobeFluorescencePolymerNanotechnologyChemistryMaterials scienceBiophysicsBiochemistryOrganic chemistryOpticsBiologyPhysicsMolecular Sensors and Ion DetectionLuminescence and Fluorescent MaterialsNanoplatforms for cancer theranostics