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Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors

Yining Tang, Chunlin Zhuang

2024Bioorganic & Medicinal Chemistry13 citationsDOIOpen Access PDF

Topics & Concepts

NecroptosisChemistryCovalent bondProgrammed cell deathEffectorCaspaseCell biologyBiochemistryEnzymeStereochemistryApoptosisBiologyOrganic chemistryCell death mechanisms and regulationMitochondrial Function and PathologyCholinesterase and Neurodegenerative Diseases
Design, synthesis and anti-necroptosis activity of fused heterocyclic MLKL inhibitors | Litcius