Copper(<scp>ii</scp>) complexes of sterically hindered phenolic Schiff bases: synthesis, characterization, interaction with biomolecules, and antioxidant and antimicrobial activity
Iveta S. Turomsha, Maxim Y. Gvozdev, Nikolai P. Osipovich, Viktoryia A. Staravoitava, Dmitriy I. Shiman, Natalia V. Loginova
Abstract
Phenolic Schiff bases and their Cu( ii ) complexes have been synthesized and characterized by physicochemical methods. The complexes exhibit low cell toxicity and high antioxidant and antibacterial activity, as evidenced by molecular docking studies.
Topics & Concepts
ChemistrySteric effectsAntimicrobialAntioxidantCopperBiomoleculeCombinatorial chemistrySchiff baseCharacterization (materials science)Organic chemistryStereochemistryPolymer chemistryNanotechnologyBiochemistryMaterials scienceMetal complexes synthesis and propertiesProtein Interaction Studies and Fluorescence AnalysisFree Radicals and Antioxidants