Porcine intestinal antimicrobial peptide as an in-feed antibiotic alternative improves intestinal digestion and immunity by shaping the gut microbiota in weaned piglets
Fengjie Ji, Huansheng Yang, Qiye Wang, Jianzhong Li, Hanlin Zhou, Shengmin Liu
Abstract
< 0.05). Collectively, dietary supplementation with a relatively low dose of PIAP (400 mg/kg from d 1 to 24; 300 mg/kg from d 25 to 37) demonstrates beneficial effects on intestinal morphology, digestive enzymes, immunity, and permeability by shaping the gut microbiota composition in weaned piglets. This study will provide a valuable reference for using PIAP as an in-feed antibiotic alternative in swine production.
Topics & Concepts
MaltaseBiologyAntibioticsAlkaline phosphataseWeaningCryptAnimal scienceRoseburiaSucraseBasal (medicine)Internal medicineSmall intestineJejunumGlucagon-like peptide-2AntimicrobialLactobacillusEndocrinologyMicrobiologyFood scienceFermentationEnzymeBiochemistryPeptideMedicineInsulinAntimicrobial Peptides and ActivitiesAnimal Nutrition and PhysiologyAquaculture disease management and microbiota