Perioperative management of a patient with severe cold agglutinin disease by using multimodal warming measures

Abstract

Cold agglutinin disease (CAD) is an autoimmune disease caused by higher titers of cold-reacting autoantibodies that lead to red blood cell (RBC) agglutination and subsequent hemolysis at low temperatures In such patients, exposure to cold can lead to hemoglobinuria and critical complications such as renal failure and myocardial damage Therefore, the prevention of perioperative hypothermia is crucial in these patients undergoing surgery. Herein, we report the successful perioperative management of a patient with severe CAD by using multimodal warming measures, as described below. Written informed consent was obtained from the patient for publication of following case.

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