Synchronous spiking of cerebellar Purkinje cells during control of movements
Ehsan Sedaghat-Nejad, Jay S. Pi, Paul Hage, Mohammad Amin Fakharian, Reza Shadmehr
Abstract
SignificanceThe information that one region of the brain transmits to another is usually viewed through the lens of firing rates. However, if the output neurons could vary the timing of their spikes, then, through synchronization, they would spotlight information that may be critical for control of behavior. Here we report that, in the cerebellum, Purkinje cell populations that share a preference for error convey, to the nucleus, when to decelerate the movement, by reducing their firing rates and temporally synchronizing the remaining spikes.
Topics & Concepts
SynchronizingNeuroscienceCerebellumPurkinje cellSynchronization (alternating current)Deep cerebellar nucleiComputer scienceControl (management)Movement (music)Cerebellar cortexBiologyPhysicsArtificial intelligenceTelecommunicationsTransmission (telecommunications)Channel (broadcasting)AcousticsVestibular and auditory disordersNeural dynamics and brain functionHearing, Cochlea, Tinnitus, Genetics