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Free Radical Mediated Oxidative Degradation of Carotenes and Xanthophylls

Raphael C. Mordi, Olabisi Theresa Ademosun, C. O. Ajanaku, Ifedolapo O. Olanrewaju, John C. Walton

2020Molecules125 citationsDOIOpen Access PDF

Abstract

This article reviews the excited-state quenching, pro-vitamin A activity and anticarcinogenicity of carotenes and xanthophylls in relation to their chemical structures. Excited-state quenching improved with the length of the conjugated chain structure. Pro-vitamin A activity was dependent on the presence of at least one beta-ionyl ring structure. The effectiveness of carotenoids as antioxidants depended on their ability to trap peroxyl radicals with production of resonance-stabilized carotenyl radicals. The products identified from oxidations of carotenes and xanthophylls with molecular oxygen and other oxidizing agents are presented. The free radical-mediated mechanisms that have been proposed to account for the different classes of products are reviewed.

Topics & Concepts

XanthophyllRadicalChemistryOxidizing agentPhotochemistryQuenching (fluorescence)Conjugated systemCaroteneExcited stateAntioxidantCarotenoidBiochemistryOrganic chemistryFluorescencePhysicsNuclear physicsQuantum mechanicsPolymerAntioxidant Activity and Oxidative StressFree Radicals and AntioxidantsPhytochemicals and Antioxidant Activities
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