Self-assembled DNA nanotrains for targeted delivery of mithramycin dimers coordinated by different metal ions: Effect of binding affinity on drug loading, release and cytotoxicity
Danfeng Wang, Min Liu, Yushu Wu, Yanna Zhao, Qingpeng Wang, Tianxin Weng, Lu Wang, He Liu, Yongfang Ren, Jun Han
Topics & Concepts
Differential scanning calorimetryCytotoxicityChemistryBiophysicsDNAEnthalpyDrug deliveryFluorescence spectroscopyFluorescenceIn vitroBiochemistryOrganic chemistryBiologyThermodynamicsPhysicsQuantum mechanicsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry