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Design, fabrication and characterization of a magnetite-chitosan coated iron-based metal–organic framework (Fe<sub>3</sub>O<sub>4</sub>@chitosan/MIL-100(Fe)) for efficient curcumin delivery as a magnetic nanocarrier

Fatemeh Parsa, Moslem Setoodehkhah, Seyed Mohammad Atyabi

2025RSC Advances17 citationsDOIOpen Access PDF

Abstract

Curcumin, a natural polyphenol with potent anticancer and anti-inflammatory properties, has significant limitations in biomedical applications due to its poor water solubility, rapid metabolism, and low bioavailability.

Topics & Concepts

ChitosanMagnetiteCharacterization (materials science)FabricationCurcuminMetalMaterials scienceGoethiteNanotechnologyChemical engineeringNuclear chemistryChemistryMetallurgyOrganic chemistryEngineeringAdsorptionAlternative medicineBiochemistryMedicinePathologyCurcumin's Biomedical ApplicationsMetal-Organic Frameworks: Synthesis and ApplicationsNanoparticle-Based Drug Delivery
Design, fabrication and characterization of a magnetite-chitosan coated iron-based metal–organic framework (Fe<sub>3</sub>O<sub>4</sub>@chitosan/MIL-100(Fe)) for efficient curcumin delivery as a magnetic nanocarrier | Litcius