A SERS-based 3D nanobiosensor: towards cell metabolite monitoring
Sara Abalde‐Cela, Rita Rebelo, Lei Wu, Ana I. Barbosa, Laura Rodríguez‐Lorenzo, Krishna Kant, Rui L. Reis, Vítor M. Correlo, Lorena Diéguez
Abstract
A biocompatible surface enhanced Raman spectroscopy (SERS) hybrid material is developed by embedding gold-based nanostructures into gellan gum “sponge-like” hydrogels, which is used for biochemical detection of disease associated cell metabolites.
Topics & Concepts
MetaboliteSurface-enhanced Raman spectroscopyGellan gumNanotechnologyBiocompatible materialChemistryBiosensorRaman spectroscopyMaterials scienceRaman scatteringBiochemistryBiomedical engineeringFood scienceMedicineOpticsPhysicsGold and Silver Nanoparticles Synthesis and ApplicationsBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniques