Molecular design to enhance binaphthyl-based chiroptics using organoboron chemistry in isomeric chiral scaffolds
Kai Zhang, Jingyi Zhao, Niu Zhang, Jin-Fa Chen, Nan Wang, Xiaodong Yin, Xiaoyan Zheng, Pangkuan Chen
Abstract
We have demonstrated a rational design strategy to improve the CPL properties of binaphthyl-based chiral systems with the aid of boron chemistry and structural modulation of the chiral scaffolds.
Topics & Concepts
Organoboron compoundsRational designBoronCombinatorial chemistryMaterials scienceChemistryStereochemistryNanotechnologyComputational chemistryOrganic chemistrySynthesis and Properties of Aromatic CompoundsOrganoboron and organosilicon chemistryAxial and Atropisomeric Chirality Synthesis