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Mollugin prevents CLP-induced sepsis in mice by inhibiting TAK1-NF-κB/MAPKs pathways and activating Keap1-Nrf2 pathway in macrophages

Xiaojun Liu, Xiaofei Shen, Han Wang, Jia‐Yi Wang, Yanlin Ren, Min Zhang, Sixu Li, Lijuan Guo, Jingyu Li, Yi Wang, Jingyu Li, Yi Wang

2023International Immunopharmacology12 citationsDOI

Topics & Concepts

SepsisNF-κBTumor necrosis factor alphaInflammationSignal transductionPharmacologyKinaseChemistryMAPK/ERK pathwayKEAP1Cancer researchMedicineImmunologyBiochemistryTranscription factorGenePharmacological Effects of Natural CompoundsInflammation biomarkers and pathwaysNF-κB Signaling Pathways
Mollugin prevents CLP-induced sepsis in mice by inhibiting TAK1-NF-κB/MAPKs pathways and activating Keap1-Nrf2 pathway in macrophages | Litcius