Targeted degradation of the enhancer lysine acetyltransferases CBP and p300
Raghu Vannam, Jan Fehmi Sayılgan, Samuel Ojeda, Barbara Karakyriakou, Eileen Hu, Johannes Kreuzer, Robert Morris, Xcanda Ixchel Herrera Lopez, Sumit Rai, Wilhelm Haas, Michael S. Lawrence, Christopher J. Ott
Topics & Concepts
EnhancerCREB-binding proteinAcetylationP300-CBP Transcription FactorsUbiquitin ligaseCereblonLysineUbiquitinChromatinCell biologyIn silicoChemistryCTCFBiologyComputational biologyTranscription factorGeneBiochemistryHistone AcetyltransferasesCREBAmino acidProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysHistone Deacetylase Inhibitors Research