Echinocandins – structure, mechanism of action and use in antifungal therapy
Mateusz Szymański, Sandra Chmielewska, Urszula Czyżewska, Marta Malinowska, Adam Tylicki
Abstract
species. In this review we summarise information about echinocandins with closer look on their chemical structure, mechanism of action, drug resistance and usage in clinical practice. We also introduce actual trends in modification of this antifungals as well as new methods of their administration, and additional use in viral and bacterial infections.
Topics & Concepts
EchinocandinsAnidulafunginCaspofunginMicafunginEchinocandinMechanism of actionDrugDrug resistanceAntifungalCombination therapyPharmacologyAntifungal drugMicrobiologyBiologyAmphotericin BFluconazoleBiochemistryIn vitroAntifungal resistance and susceptibilityFungal Infections and StudiesPlant-Microbe Interactions and Immunity