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Evaluation of covariate effects using forest plots and introduction to the <i>coveffectsplot</i> R package

Jean‐Francois Marier, Nathan S. Teuscher, Samer Mouksassi

2022CPT Pharmacometrics & Systems Pharmacology28 citationsDOIOpen Access PDF

Abstract

The current tutorial describes why forest plots are needed for an effective communication of covariates effects, how they are constructed, and how they should be presented. Simulation-based methodologies allowing the user to evaluate the marginal impact of changing one covariate at a time or by considering the joint effects of correlated covariates are introduced along with graphical tools for an optimal assessment of the covariate effects. The R package coveffectsplot and an associated R Shiny application are provided to facilitate the design and construction of forest plots for the visualization of covariate effects. All codes and materials are available on a public Github repository.

Topics & Concepts

CovariateR packageComputer scienceVisualizationStatisticsEconometricsData miningMathematicsMachine learningForest ecology and managementData Analysis with RSoil Geostatistics and Mapping
Evaluation of covariate effects using forest plots and introduction to the <i>coveffectsplot</i> R package | Litcius