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Electron beam scattering device for FLASH preclinical studies with 6-MeV LINAC

Dong Hyeok Jeong, Manwoo Lee, H. Lim, Sang Koo Kang, Sangjin Lee, Hee Chang Kim, Kyohyun Lee, Seung Heon Kim, Dong-Eun Lee, Kyoung Won Jang

2020Nuclear Engineering and Technology20 citationsDOIOpen Access PDF

Abstract

In this study, an electron-scattering device was fabricated to practically use the ultra-high dose rate electron beams for the FLASH preclinical research in Dongnam Institute of Radiological and Medical Sciences. The Dongnam Institute of Radiological and Medical Sciences has been involved in the investigation of linear accelerators for preclinical research and has recently implemented FLASH electron beams. To determine the geometry of the scattering device for the FLASH preclinical research with a 6-MeV linear accelerator, the Monte Carlo N-particle transport code was exploited. By employing the fabricated scattering device, the off-axis and depth dose distributions were measured with radiochromic films. The generated mean energy of electron beams via the scattering device was 4.3 MeV, and the symmetry and flatness of the off-axis dose distribution were 0.11% and 2.33%, respectively. Finally, the doses per pulse were obtained as a function of the source to surface distance (SSD); the measured dose per pulse varied from 4.0 to 0.2 Gy/pulse at an SSD range of 20–90 cm. At an SSD of 30 cm with a 100-Hz repetition rate, the dose rate was 180 Gy/s, which is sufficient for the preclinical FLASH studies.

Topics & Concepts

Linear particle acceleratorScatteringFlash (photography)Monte Carlo methodMaterials scienceCathode rayElectronElectron scatteringParticle acceleratorOpticsDose ratePhysicsBeam (structure)Atomic physicsNuclear physicsMedical physicsMathematicsStatisticsRadiation Therapy and DosimetryRadiation Detection and Scintillator TechnologiesAdvanced Radiotherapy Techniques
Electron beam scattering device for FLASH preclinical studies with 6-MeV LINAC | Litcius